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Original Research Article | OPEN ACCESS

Effect of fallopian tube dredging with a combination of hysteroscopy and Traditional Chinese medicine containing marine-derived principles in patients with inflammatory obstruction of fallopian tube

Meng-meng Li1, Wei-juan Wang2, Feng Huang3, Xiao Wang4

1Department of Obstetrics and Gynecology, Weifang Maternal and Child Health Hospital, Weifang 261041; 2Department of Gynecology, Lin Yi Coal Hot Spring Sanatorium of Shandong Province, Linyi 276032; 3Department of Gynecology, Jimo District People's Hospital, Qingdao 266200; 4Department of Gynecology, Anqiu People's Hospital, Weifang 262100, Shandong Province, China.

For correspondence:-  Xiao Wang   Email: zanzianyue7372666@163.com

Accepted: 22 April 2021        Published: 31 May 2021

Citation: Li M, Wang W, Huang F, Wang X. Effect of fallopian tube dredging with a combination of hysteroscopy and Traditional Chinese medicine containing marine-derived principles in patients with inflammatory obstruction of fallopian tube. Trop J Pharm Res 2021; 20(5):1079-1083 doi: 10.4314/tjpr.v20i5.28

© 2021 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To investigate the therapeutic effect of fallopian tube dredging using a combination of hysteroscopy and Traditional Chinese Medicine (TCM) containing marine-derived bioactive principles on patients with inflammatory obstruction of fallopian tube.
Methods: A total of 108 patients with inflammatory obstruction of fallopian tube admitted to Weifang Maternal and Child Health Hospital from February 2017 to February 2018 were enrolled in the study. The patients were randomized into study group (n = 54) and reference group (n = 54). The reference group received traditional laparotomy, while the study group received fallopian tube dredging using hysteroscopy in combination with TCM containing marine-based bioactive principles. The clinical effects of the two treatments were compared.
Results: The number of completely unobstructed patients was significantly higher in the study group than in the reference group, with lower number of patients unilaterally unobstructed in the study group (p < 0.05). No significant differences in the number of bilaterally obstructed patients between the two groups were observed (p > 0.05). The study group showed an evidently higher total effectiveness rate than the reference group (p < 0.05). Stronger evidence of a higher number of cases of intrauterine pregnancy in the study group than that in the reference group was found, while a strikingly lower number of pregnancy failures and ectopic gestations in the study group was obtained, when compared to the reference group (p < 0.05).
Conclusion: Fallopian tube dredging combined with hysteroscopy and TCM containing marine-derived principles effectively improves treatment outcomes in patients with fallopian tube obstruction. Thus, the combination therapy has greater benefits than the traditional approach.

Keywords: Fallopian tube, Inflammatory obstruction, Dredging with hysteroscopy, TCM, Marine-derived principles

Impact Factor
Thompson Reuters (ISI): 0.523 (2021)
H-5 index (Google Scholar): 39 (2021)

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